This page shows how many targets have made it to each experimental stage. It only counts the 'best' form of each target, even if the target has been cloned and expressed multiple times. I.e. if an expressed target is found to be insoluble, and later another expression system makes a soluble form of the target, the target only appears once as 'expressed' and 'soluble'.
These totals include progress on full length ORF targets as well as domain targets. Most domain targets have been stopped while we re-evaluate the purification protocols and domain boundary predictions.
Data last updated 2007-02-20 10:55:12 PST8PDT
| Experimental Stage | Number of Targets/Structures |
|---|---|
| Selected | 1036 |
| Cloned | 900 |
| Expression tested | 874 |
| Solubility tested | 600 |
| Solubility tested (Soluble) | 423 |
| Solubility tested (Insoluble) | 177 |
| Purified | 242 |
| Crystallized | 96 |
| Diffraction quality crystals | 72 |
| Native diffraction data | 42 |
| Phasing diffraction data | 61 |
| Traceable map | 59 |
| Crystal structure | 90 structures / 59 targets |
| NMR characterization | 47 |
| HSQC | 22 |
| NMR structure | 4 structures / 4 targets |
| In PDB | 92 structures / 62 targets |
| Biochemical function | 15 |
| Work stopped | 755 |